Gene Report

CD70 — Single Gene Characterization

This report provides a multi-faceted characterization of CD70 across the CoMMpass cohort: expression distribution, survival stratification, cytogenetic context, and co-expression correlations.

Generated with gene_report("CD70"). See ?gene_report for usage.

Expression Distribution

VST-normalized expression values across all samples, showing the distribution shape and central tendency.

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Survival by Expression

Patients split at median CD70 expression into High/Low groups.

Expression by Cytogenetic Subtype

Boxplots comparing expression levels across FISH-defined cytogenetic marker groups (t(4;14), t(14;16), del(17p)).

Data not available: Target vig_gene_expr_subtype returned NULL. See Data Sources.

Gene-Gene Correlations

Top correlated genes with CD70 (Pearson, VST expression).

Data Sources

Results in this vignette are derived from the MMRF CoMMpass study (MMRF-COMMPASS, ~1,143 patients), downloaded via TCGAbiolinks. The pipeline runs with a configurable sample_limit (default 200; CI uses 20).

For full citations, data access tiers, and the distinction between pipeline data and synthetic test data, see the Data Sources vignette.

Recent Changes

Recent project commits with lines added, files changed, and change categories.

Reproducibility

Session Info (click to expand)
Show code
sessionInfo()
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